BDBM50338614 CHEMBL1683960::N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-(3-(morpholinomethyl)phenyl)pyrimidin-4-amine

SMILES Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1-c1cccc(CN2CCOCC2)c1

InChI Key InChIKey=GKWOYHUYOVPTDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50338614   

TargetEpidermal growth factor receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50338614(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-...)
Affinity DataIC50: 590nMAssay Description:Inhibition of EGFR by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50338614(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-...)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of HER2 by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed