BDBM50339154 (2S)-5,7-dihydroxy-4'-methoxy-8-prenylflavanone::(S)-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)chroman-4-one::CHEMBL556429

SMILES [#6]-[#8]-c1ccc(cc1)-[#6@@H]-1-[#6]-[#6](=O)-c2c(-[#8])cc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2-[#8]-1

InChI Key InChIKey=OJBCFFFLDBSSRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339154   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50339154((2S)-5,7-dihydroxy-4'-methoxy-8-prenylflavanone | ...)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed