BDBM50339333 CHEMBL1688085::N-[1-Ethyl-1-(3-fluorophenyl)propyl]-7,7-dimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide

SMILES CCC(CC)(NC(=O)c1cnn2c1NC(CC2(C)C)c1ccccc1)c1cccc(F)c1

InChI Key InChIKey=AFJKHMXICXLERW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339333   

TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50339333(N-[1-Ethyl-1-(3-fluorophenyl)propyl]-7,7-dimethyl-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of CaSR expressed in CHO cells incubated with compound for 10 mins measured after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed