BDBM50339334 CHEMBL1688086::N-[1-Ethyl-1-(2-fluorophenyl)propyl]-7,7-dimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide

SMILES CCC(CC)(NC(=O)c1cnn2c1NC(CC2(C)C)c1ccccc1)c1ccccc1F

InChI Key InChIKey=ILUFJJNLTHNZPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339334   

TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50339334(N-[1-Ethyl-1-(2-fluorophenyl)propyl]-7,7-dimethyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of CaSR expressed in CHO cells incubated with compound for 10 mins measured after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed