BDBM50339383 (+/-)-3-(4-Chlorophenyl)-3-{[1-(hydroxymethyl)cyclopropyl]methoxy}-2-[4-(trifluoromethyl)benzyl]isoindolin-1-one::CHEMBL1688288

SMILES OCC1(COC2(N(Cc3ccc(cc3)C(F)(F)F)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=IISARDHLGBCHQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339383   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339383BDBM50339383((+/-)-3-(4-Chlorophenyl)-3-{[1-(hydroxymethyl)cycl...)
Affinity DataIC50: 2.14E+5nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed