BDBM50339570 4'-(1-Phenylsulfanylmethyl-1H-[1,2,3]triazol-4-yl)-biphenyl-3-ol::CHEMBL1688765

SMILES Oc1cccc(c1)-c1ccc(cc1)-c1cn(CSc2ccccc2)nn1

InChI Key InChIKey=YUEWKJSWFAGEJD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50339570   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339570BDBM50339570(4'-(1-Phenylsulfanylmethyl-1H-[1,2,3]triazol-4-yl)...)
Affinity DataIC50: 400nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339570BDBM50339570(4'-(1-Phenylsulfanylmethyl-1H-[1,2,3]triazol-4-yl)...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProstaglandin E synthase 2(Human)
University of Salerno

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339570BDBM50339570(4'-(1-Phenylsulfanylmethyl-1H-[1,2,3]triazol-4-yl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL1-beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed