BDBM50339574 5-Dimethylamino-naphthalene-1-sulfonic acid{4'-[1-(3-phenyl-propyl)-1H-[1,2,3]triazol-4-yl]-biphenyl-4-yl}-amide::CHEMBL1688773

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(cc1)-c1ccc(cc1)-c1cn(CCCc2ccccc2)nn1

InChI Key InChIKey=PEFYOGCDOOKRFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50339574   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339574(5-Dimethylamino-naphthalene-1-sulfonic acid{4'-[1-...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339574(5-Dimethylamino-naphthalene-1-sulfonic acid{4'-[1-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339574(5-Dimethylamino-naphthalene-1-sulfonic acid{4'-[1-...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed