BDBM50339576 4-(5-Benzyl-3-phenylsulfanylmethyl-3H-[1,2,3]triazol-4-yl)-benzaldehyde::CHEMBL1688775

SMILES O=Cc1ccc(cc1)-c1c(Cc2ccccc2)nnn1CSc1ccccc1

InChI Key InChIKey=OYMAQWCXOHAWNM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50339576   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50339576(4-(5-Benzyl-3-phenylsulfanylmethyl-3H-[1,2,3]triaz...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProstaglandin E synthase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50339576(4-(5-Benzyl-3-phenylsulfanylmethyl-3H-[1,2,3]triaz...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL1-beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50339576(4-(5-Benzyl-3-phenylsulfanylmethyl-3H-[1,2,3]triaz...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed