BDBM50339578 Benzoic acid 1-Phenylsulfanylmethyl-1H-[1,2,3]Triazol-4-ylmethyl Ester::CHEMBL1688767

SMILES O=C(OCc1cn(CSc2ccccc2)nn1)c1ccccc1

InChI Key InChIKey=ZCKKMLHAEFAROR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50339578   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50339578(Benzoic acid 1-Phenylsulfanylmethyl-1H-[1,2,3]Tria...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProstaglandin E synthase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50339578(Benzoic acid 1-Phenylsulfanylmethyl-1H-[1,2,3]Tria...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL1-beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50339578(Benzoic acid 1-Phenylsulfanylmethyl-1H-[1,2,3]Tria...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed