BDBM50339580 4'-[1-(3-Phenyl-propyl)-1H-[1,2,3]triazol-4-yl]-biphenyl-4-ol::CHEMBL1688768

SMILES Oc1ccc(cc1)-c1ccc(cc1)-c1cn(CCCc2ccccc2)nn1

InChI Key InChIKey=NIXYIYZZGPOGPX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50339580   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50339580(4'-[1-(3-Phenyl-propyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50339580(4'-[1-(3-Phenyl-propyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProstaglandin E synthase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50339580(4'-[1-(3-Phenyl-propyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL1-beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed