BDBM50339592 2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imidazol-5(4H)-one::CHEMBL603189

SMILES COc1cc(C=C2N=C(N)NC2=O)ccc1O

InChI Key InChIKey=CWWKTGHWIFDKSB-UHFFFAOYSA-N

Data  6 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50339592   

TargetDual specificity protein kinase CLK4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataIC50: 470nMAssay Description:Inhibition of human CLK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataIC50: 470nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataIC50: 640nMAssay Description:Inhibition of human CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  890nMAssay Description:Inhibition of Cryptococcus neoformans recombinant Can2 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  910nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv3273 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  920nMAssay Description:Inhibition of Candida albicans recombinant Nce103 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human CLK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  9.60E+3nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  1.05E+4nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  1.18E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed