BDBM50339738 (5R)-N-[1-(4-Chloro-3-methoxyphenyl)-1-ethylpropyl]-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]-pyrimidine-3-carboxamide hydrochloride::CHEMBL1687956

SMILES CCC(CC)(NC(=O)c1c(C)nn2c1N[C@H](CC2(C)C)c1ccccc1)c1ccc(Cl)c(OC)c1

InChI Key InChIKey=JLEZSBMMOUKCMD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339738   

TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50339738((5R)-N-[1-(4-Chloro-3-methoxyphenyl)-1-ethylpropyl...)
Affinity DataIC50: 6.10nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as inhibition of [35S]GTPgammaS binding after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed