BDBM50339823 CHEMBL1761090::N-((2S)-3-(8',9'-dihydro-3'H-spiro[piperidine-3,7'-pyrano[3,2-e]indazole]-1-yl)-2-hydroxypropyl)-N-(2-ethoxyethyl)-2,6-dimethylbenzenesulfonamide

SMILES CCOCCN(C[C@@H](O)CN1CCCC2(CCc3c(O2)ccc2[nH]ncc32)C1)S(=O)(=O)c1c(C)cccc1C

InChI Key InChIKey=ZSKFBGIRLVOQAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339823   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50339823(N-((2S)-3-(8',9'-dihydro-3'H-spiro[piperidine-3,7'...)
Affinity DataIC50: 9nMAssay Description:Inhibition of AKT1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50339823(N-((2S)-3-(8',9'-dihydro-3'H-spiro[piperidine-3,7'...)
Affinity DataIC50: 44nMAssay Description:Inhibition of AKT1 in human LNCaP cells assessed as PRAS40 phosphorylation at Thr246 after 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed