BDBM50339827 CHEMBL1761084::N-(2-ethoxyethyl)-N-((2S)-2-hydroxy-3-(6-hydroxyspiro[chroman-2,3'-piperidine]-1'-yl)propyl)-3,5-dimethylisoxazole-4-sulfonamide

SMILES CCOCCN(C[C@@H](O)CN1CCCC2(CCc3cc(O)ccc3O2)C1)S(=O)(=O)c1c(C)noc1C

InChI Key InChIKey=AZWFENCKMNSKBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339827   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50339827(N-(2-ethoxyethyl)-N-((2S)-2-hydroxy-3-(6-hydroxysp...)
Affinity DataIC50: 70nMAssay Description:Inhibition of AKT1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50339827(N-(2-ethoxyethyl)-N-((2S)-2-hydroxy-3-(6-hydroxysp...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of AKT1 in human LNCaP cells assessed as PRAS40 phosphorylation at Thr246 after 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed