BDBM50339831 CHEMBL1761083::N-(2-ethoxyethyl)-N-((2S)-2-hydroxy-3-(6-hydroxy-4-oxospiro[chroman-2,3'-piperidine]-1'-yl)propyl)-2,6-dimethylbenzenesulfonamide

SMILES CCOCCN(C[C@@H](O)CN1CCCC2(C1)CC(=O)c1cc(O)ccc1O2)S(=O)(=O)c1c(C)cccc1C

InChI Key InChIKey=ONZIIEDMJXLRAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339831   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50339831(N-(2-ethoxyethyl)-N-((2S)-2-hydroxy-3-(6-hydroxy-4...)
Affinity DataIC50: 300nMAssay Description:Inhibition of AKT1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50339831(N-(2-ethoxyethyl)-N-((2S)-2-hydroxy-3-(6-hydroxy-4...)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of AKT1 in human LNCaP cells assessed as PRAS40 phosphorylation at Thr246 after 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed