BDBM50339919 CHEMBL1761661::trans-rac-1-(2-(7-chloro-1-isobutyl-5-(2-methoxyphenyl)-2-oxo-4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)acetyl)piperidine-4-carboxylic acid

SMILES COc1ccccc1[C@H]1CN(CC(=O)N2CCC(CC2)C(O)=O)C(=O)[C@H](CC(C)C)c2ccc(Cl)cc12

InChI Key InChIKey=UIDVDWBJUGYMJC-JWQCQUIFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339919   

TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339919(CHEMBL1761661 | trans-rac-1-(2-(7-chloro-1-isobuty...)
Affinity DataIC50:  500nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed