BDBM50339967 CHEMBL1762313::N-(3-(4-(benzyl(4-bromophenyl)amino)piperidin-1-yl)butyl)-3,5-dichloroisonicotinamide

SMILES CC(CCNC(=O)c1c(Cl)cncc1Cl)N1CCC(CC1)N(Cc1ccccc1)c1ccc(Br)cc1

InChI Key InChIKey=NKCYWBUHTRUFPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339967   

TargetC-C chemokine receptor type 5(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50339967(N-(3-(4-(benzyl(4-bromophenyl)amino)piperidin-1-yl...)
Affinity DataIC50: 30nMAssay Description:Displacement of [128I]-RANTES from CCR5 expressed in HEK293F cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50339967(N-(3-(4-(benzyl(4-bromophenyl)amino)piperidin-1-yl...)
Affinity DataIC50: 49nMAssay Description:Antagonist activity against human CCR5 assessed as inhibition of HIV1 gp120-induced cell-cell fusion between human HeLa P4/R5 cells and CHO-tat10 cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed