BDBM50340093 1-(4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)ethanone::CHEMBL1762675

SMILES COc1ccc(cc1)C1NC(=S)N=C(C)C1C(C)=O

InChI Key InChIKey=BFKQGJLLYFERDF-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340093   

TargetCarbonic anhydrase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50340093(1-(4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-t...)
Affinity DataKi:  31nMAssay Description:Binding affinity to human CA2 assessed as inhibition constant using 4-nitrophenylacetate as substrate by spectrophotometrical analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50340093(1-(4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-t...)
Affinity DataKi:  47nMAssay Description:Binding affinity to human CA1 assessed as inhibition constant using 4-nitrophenylacetate as substrate by spectrophotometrical analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Shaoyang University

Curated by ChEMBL
LigandPNGBDBM50340093(1-(4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-t...)
Affinity DataIC50: 2.51E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed