BDBM50340120 CHEMBL1760034::N2-(naphthalen-2-yl)-N4-(3,4,5-trimethoxyphenyl)-1,3,5-triazine-2,4-diamine

SMILES COc1cc(Nc2ncnc(Nc3ccc4ccccc4c3)n2)cc(OC)c1OC

InChI Key InChIKey=QLHPKTYPPJIUFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340120   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50340120(CHEMBL1760034 | N2-(naphthalen-2-yl)-N4-(3,4,5-tri...)
Affinity DataIC50:  409nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50340120(CHEMBL1760034 | N2-(naphthalen-2-yl)-N4-(3,4,5-tri...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed