BDBM50340140 CHEMBL1760054::N2-(3-chlorophenyl)-N4-(quinolin-3-yl)pyrimidine-2,4-diamine

SMILES Clc1cccc(Nc2nccc(Nc3cnc4ccccc4c3)n2)c1

InChI Key InChIKey=AAHOZWNLWKBWNN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340140   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50340140(CHEMBL1760054 | N2-(3-chlorophenyl)-N4-(quinolin-3...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50340140(CHEMBL1760054 | N2-(3-chlorophenyl)-N4-(quinolin-3...)
Affinity DataIC50:  3.38E+3nMAssay Description:Inhibition of IGF1-induced human IGF1R auto phosphorylation expressed in mouse NIH-3T3 cells preincubated with compound for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed