BDBM50340145 3-chloro-N-(((3S,4S)-1-(3,4-dimethoxyphenethyl)-4-(4-methoxyphenyl)pyrrolidin-3-yl)methyl)benzamide::CHEMBL1760059::rac-3-cyano-N-(((3S,4S)-1-(3,4-dimethoxyphenethyl)-4-(4-methoxyphenyl)pyrrolidin-3-yl)methyl)benzamide

SMILES COc1ccc(cc1)[C@H]1CN(CCc2ccc(OC)c(OC)c2)C[C@@H]1CNC(=O)c1cccc(Cl)c1

InChI Key InChIKey=IHXFHHOZRJEQBX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50340145   

LigandPNGBDBM50340145(3-chloro-N-(((3S,4S)-1-(3,4-dimethoxyphenethyl)-4-...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at MCHR1 by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340145(3-chloro-N-(((3S,4S)-1-(3,4-dimethoxyphenethyl)-4-...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at MCHR1 by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340145(3-chloro-N-(((3S,4S)-1-(3,4-dimethoxyphenethyl)-4-...)
Affinity DataIC50: 160nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in human HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340145(3-chloro-N-(((3S,4S)-1-(3,4-dimethoxyphenethyl)-4-...)
Affinity DataIC50: 160nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in human HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340145(3-chloro-N-(((3S,4S)-1-(3,4-dimethoxyphenethyl)-4-...)
Affinity DataIC50: 250nMAssay Description:Displacement of [125I]-MCH from MCHR1 after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340145(3-chloro-N-(((3S,4S)-1-(3,4-dimethoxyphenethyl)-4-...)
Affinity DataIC50: 250nMAssay Description:Displacement of [125I]-MCH from MCHR1 after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed