BDBM50340191 CHEMBL1760237::rac-3-chloro-N-(2-((3R,4S)-1-(3,4-dimethoxyphenethyl)-4-(4-methoxyphenyl)pyrrolidin-3-yl)ethyl)benzamide

SMILES COc1ccc(cc1)[C@H]1CN(CCc2ccc(OC)c(OC)c2)C[C@@H]1CCNC(=O)c1cccc(Cl)c1

InChI Key InChIKey=GGPDSNHLDADOIF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340191   

LigandPNGBDBM50340191(rac-3-chloro-N-(2-((3R,4S)-1-(3,4-dimethoxypheneth...)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at MCHR1 by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340191(rac-3-chloro-N-(2-((3R,4S)-1-(3,4-dimethoxypheneth...)
Affinity DataIC50: 56nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in human HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340191(rac-3-chloro-N-(2-((3R,4S)-1-(3,4-dimethoxypheneth...)
Affinity DataIC50: 77nMAssay Description:Displacement of [125I]-MCH from MCHR1 after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed