BDBM50340197 CHEMBL1760243::rac-6-chloro-2-(2-((3R,4S)-1-(3,4-dimethoxyphenethyl)-4-(4-methoxyphenyl)pyrrolidin-3-yl)ethyl)-1H-benzo[d]imidazole

SMILES COc1ccc(cc1)[C@H]1CN(CCc2ccc(OC)c(OC)c2)C[C@@H]1CCc1nc2ccc(Cl)cc2[nH]1

InChI Key InChIKey=LLWKBGRAWPNWFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340197   

LigandPNGBDBM50340197(rac-6-chloro-2-(2-((3R,4S)-1-(3,4-dimethoxypheneth...)
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in human HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340197(rac-6-chloro-2-(2-((3R,4S)-1-(3,4-dimethoxypheneth...)
Affinity DataIC50: 91nMAssay Description:Antagonist activity at MCHR1 by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340197(rac-6-chloro-2-(2-((3R,4S)-1-(3,4-dimethoxypheneth...)
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]-MCH from MCHR1 after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed