BDBM50340200 CHEMBL1760246::N-(3-chlorophenyl)-2-((3R,4S)-4-(4-methoxyphenyl)-1-(2-(tetrahydro-2H-pyran-4-yl)ethyl)pyrrolidin-3-yl)acetamide

SMILES COc1ccc(cc1)[C@H]1CN(CCC2CCOCC2)C[C@@H]1CC(=O)Nc1cccc(Cl)c1

InChI Key InChIKey=KGFPROOGUUWDFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340200   

LigandPNGBDBM50340200(N-(3-chlorophenyl)-2-((3R,4S)-4-(4-methoxyphenyl)-...)
Affinity DataIC50: 21nMAssay Description:Displacement of [125I]-MCH from MCHR1 after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340200(N-(3-chlorophenyl)-2-((3R,4S)-4-(4-methoxyphenyl)-...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at MCHR1 by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340200(N-(3-chlorophenyl)-2-((3R,4S)-4-(4-methoxyphenyl)-...)
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in human HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed