BDBM50340205 CHEMBL1760251::N-(3-chlorophenyl)-2-((3R,4S)-4-(4-methoxyphenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)pyrrolidin-3-yl)acetamide

SMILES COc1ccc(cc1)[C@H]1CN(CCCN2CCCC2=O)C[C@@H]1CC(=O)Nc1cccc(Cl)c1

InChI Key InChIKey=LXUYAULCTIKKQB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340205   

LigandPNGBDBM50340205(N-(3-chlorophenyl)-2-((3R,4S)-4-(4-methoxyphenyl)-...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at MCHR1 by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340205(N-(3-chlorophenyl)-2-((3R,4S)-4-(4-methoxyphenyl)-...)
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]-MCH from MCHR1 after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50340205(N-(3-chlorophenyl)-2-((3R,4S)-4-(4-methoxyphenyl)-...)
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in human HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed