BDBM50340434 (4-(1H-pyrazol-3-yl)piperidin-1-yl)(3,4-dihydroquinolin-1(2H)-yl)methanone::CHEMBL1761847

SMILES O=C(N1CCC(CC1)c1ccn[nH]1)N1CCCc2ccccc12

InChI Key InChIKey=RKYLSXVZXXFFEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340434   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340434((4-(1H-pyrazol-3-yl)piperidin-1-yl)(3,4-dihydroqui...)
Affinity DataIC50: 127nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabeled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340434((4-(1H-pyrazol-3-yl)piperidin-1-yl)(3,4-dihydroqui...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabeled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed