BDBM50340443 (3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(4-methyl-3,4-dihydroquinoxalin-1(2H)-yl)methanone::CHEMBL1761864

SMILES CN1CCN(C(=O)N2CCC(C2)c2cn[nH]c2)c2ccccc12

InChI Key InChIKey=BZXHBXVWXIMYMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340443   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340443((3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(4-methyl-3,4-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabeled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340443((3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(4-methyl-3,4-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabeled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed