BDBM50340503 1-((2-aminopyridin-4-yl)methyl)-5,5-dimethyl-3-(4-(trifluoromethylthio)phenyl)imidazolidine-2,4-dione::CHEMBL1762179

SMILES CC1(C)N(Cc2ccnc(N)c2)C(=O)N(C1=O)c1ccc(SC(F)(F)F)cc1

InChI Key InChIKey=SPKNFLLCBPBCIV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340503   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50340503(1-((2-aminopyridin-4-yl)methyl)-5,5-dimethyl-3-(4-...)
Affinity DataIC50:  92nMAssay Description:Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in SF21 cells after 10 mins by time resolved-fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50340503(1-((2-aminopyridin-4-yl)methyl)-5,5-dimethyl-3-(4-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of autophosphosphorylation of human IGF1R expressed in IGF1-stimulated MCF7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50340503(1-((2-aminopyridin-4-yl)methyl)-5,5-dimethyl-3-(4-...)
Affinity DataIC50:  92nMAssay Description:Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in SF21 cells by time resolved-fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed