BDBM50340528 (S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzyl)-5-(2-(phenoxymethyl)azetidin-1-ylsulfonyl)indoline-2,3-dione::CHEMBL1762348

SMILES FCCOCCOCCOc1ccc(CN2C(=O)C(=O)c3cc(ccc23)S(=O)(=O)N2CC[C@H]2COc2ccccc2)cc1

InChI Key InChIKey=RHNPIGHUWVOJIW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50340528   

TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50340528((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50: 19.2nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50340528((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50: 26.9nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50340528((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50: 2.99E+3nMAssay Description:Inhibition of caspase 6 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-1(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50340528((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of caspase 1 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50340528((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of caspase 8 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed