BDBM50340552 (3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl)(2-methoxyethyl)amino)-4-methylphenyl)methanol::CHEMBL1762549

SMILES COCCN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C

InChI Key InChIKey=HVLNVFOAUCUYQK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50340552   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50340552((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human EPHB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50340552((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50340552((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...)
Affinity DataIC50: 390nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50340552((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...)
Affinity DataIC50: 720nMAssay Description:Inhibition FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed