BDBM50340556 (3-((2-(3-methoxy-5-morpholinophenylamino)pyrimidin-4-yl)(methyl)amino)-4-methylphenyl)methanol::CHEMBL1762545

SMILES COc1cc(Nc2nccc(n2)N(C)c2cc(CO)ccc2C)cc(c1)N1CCOCC1

InChI Key InChIKey=WRFJDMAYWYYANT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340556   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50340556((3-((2-(3-methoxy-5-morpholinophenylamino)pyrimidi...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human EPHB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50340556((3-((2-(3-methoxy-5-morpholinophenylamino)pyrimidi...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed