BDBM50340883 (4-amino-2-(pyridin-3-ylamino)thiazol-5-yl)(pyridin-2-yl)methanone::CHEMBL1761805

SMILES Nc1nc(Nc2cccnc2)sc1C(=O)c1ccccn1

InChI Key InChIKey=NXLLJUGNPKTXQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340883   

TargetCyclin-dependent kinase 5 activator 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50340883((4-amino-2-(pyridin-3-ylamino)thiazol-5-yl)(pyridi...)
Affinity DataIC50: 800nMAssay Description:Inhibition of CDK5/p25 assessed as [33P]gamma-ATP incorporation into peptide PKTPKKAKKL substrate after 45 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed