BDBM50341125 CHEMBL1760371::N-(3-tert-butyl-5-(4-methyl-1H-imidazol-1-yl)phenyl)-4-methyl-3-(4-(pyridin-3-yl)thiazol-2-ylamino)benzamide

SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nc(cs3)-c3cccnc3)c2)cc(c1)C(C)(C)C

InChI Key InChIKey=YKDNQUNPTIJKCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341125   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341125(N-(3-tert-butyl-5-(4-methyl-1H-imidazol-1-yl)pheny...)
Affinity DataIC50: 20.1nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed