BDBM50341165 (+/-)-(3R,4S,5S)-3-(3-Isopropyl-benzylami no)-1,1-dioxo-5-(3-propoxymethyl-be nzyl)-hexahydro-1lambda*6*-thiopyra n-4-ol::CHEMBL1760734

SMILES CCCOCc1cccc(C[C@@H]2CS(=O)(=O)C[C@H](NCc3cccc(c3)C(C)C)[C@H]2O)c1

InChI Key InChIKey=AEZXMYXSAYELNI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341165   

TargetCathepsin D(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50341165((+/-)-(3R,4S,5S)-3-(3-Isopropyl-benzylami no)-1,1-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50341165((+/-)-(3R,4S,5S)-3-(3-Isopropyl-benzylami no)-1,1-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed