BDBM50341191 CHEMBL1760888::cis-N-((1S,3R)-3-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-ylcarbamoyl)cyclopentyl)-3-(trifluoromethyl)benzamide

SMILES CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)[C@@H]3CC[C@@H](C3)NC(=O)c3cccc(c3)C(F)(F)F)sc12

InChI Key InChIKey=NCWRSHWNMYHJMN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341191   

TargetAdenosine receptor A2b(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341191(cis-N-((1S,3R)-3-(7-(N-ethylacetamido)-4-methoxybe...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human adenosine A2B receptor expressed in CHO cells assessed as decrease in cellular cAMP level after 20 to 25 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341191(cis-N-((1S,3R)-3-(7-(N-ethylacetamido)-4-methoxybe...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341191(cis-N-((1S,3R)-3-(7-(N-ethylacetamido)-4-methoxybe...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed