BDBM50341238 4-(methacrylamidomethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide::CHEMBL1765719

SMILES CC(=C)C(=O)NCc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1

InChI Key InChIKey=WLOZWKJGFIDROX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341238   

TargetMast/stem cell growth factor receptor Kit(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341238(4-(methacrylamidomethyl)-N-(4-methyl-3-(4-(pyridin...)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341238(4-(methacrylamidomethyl)-N-(4-methyl-3-(4-(pyridin...)
Affinity DataIC50: 4.11E+3nMAssay Description:Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341238(4-(methacrylamidomethyl)-N-(4-methyl-3-(4-(pyridin...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human wild type ABL1 assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed