BDBM50341414 CHEMBL4176338::US11534443, Example 23

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1cc(OC2CCCC2)c2nc(N)nc(C)c2c1

InChI Key InChIKey=LCKPXRGDNVKPOQ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341414   

TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent

LigandBDBM50341414(CHEMBL4176338 | US11534443, Example 23)Copy SMILESCopy InChI

Affinity DataIC50: 1.10nMAssay Description:The Kinase-Glo Kinase Assay Kit was purchased from Promega. All assays were performed at room temperature using white OptiPlate -384 well plate. The ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/20/2023
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Peking Union Medical College

Curated by ChEMBL

LigandBDBM50341414(CHEMBL4176338 | US11534443, Example 23)Copy SMILESCopy InChI

Affinity DataIC50: 1.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate by Kinase-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/14/2020
Entry Details Article
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