BDBM50341771 4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)amino]-pyrimidin-2-yl}piperazine-1-carboxylic Acid Methyl Ester::CHEMBL1766889

SMILES COC(=O)N1CCN(CC1)c1ncc(NC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2)cn1

InChI Key InChIKey=DLCZOOQVYHOLGV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341771   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341771(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341771(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  410nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed