BDBM50341776 CHEMBL1766805::N-(4-(1-(cyclopropanecarbonyl)piperidin-4-yl)phenyl)-2-phenyl-5-(trifluoromethyl)oxazole-4-carboxamide

SMILES FC(F)(F)c1oc(nc1C(=O)Nc1ccc(cc1)C1CCN(CC1)C(=O)C1CC1)-c1ccccc1

InChI Key InChIKey=RAAQQBQIMGEXBY-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341776   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341776(CHEMBL1766805 | N-(4-(1-(cyclopropanecarbonyl)pipe...)
Affinity DataIC50:  67nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341776(CHEMBL1766805 | N-(4-(1-(cyclopropanecarbonyl)pipe...)
Affinity DataEC50:  362nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed