BDBM50341825 2-(4-(benzyloxy)phenyl)-N-hydroxy-1-oxo-2,3-dihydro-1H-pyrrolo[3,4-c]quinoline-4-carboxamide::CHEMBL1766896

SMILES ONC(=O)c1nc2ccccc2c2C(=O)N(Cc12)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=AUSYXXOLFARXLL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341825   

LigandPNGBDBM50341825(2-(4-(benzyloxy)phenyl)-N-hydroxy-1-oxo-2,3-dihydr...)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human ADAMTS-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50341825(2-(4-(benzyloxy)phenyl)-N-hydroxy-1-oxo-2,3-dihydr...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant aggrecanase 1 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341825(2-(4-(benzyloxy)phenyl)-N-hydroxy-1-oxo-2,3-dihydr...)
Affinity DataIC50: 950nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341825(2-(4-(benzyloxy)phenyl)-N-hydroxy-1-oxo-2,3-dihydr...)
Affinity DataIC50: 950nMAssay Description:Inhibition of recombinant human ADAMTS-5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed