BDBM50342174 CHEMBL1766175::rac-1-(4'-Chloro[1,1'-biphenyl]-4-yl)-1-(1H-imidazol-4-yl)-2-methyl-1-propanol

SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=SVOSCUAPCVQCPN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342174   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342174(rac-1-(4'-Chloro[1,1'-biphenyl]-4-yl)-1-(1H-imidaz...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human 17,20 lyase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342174(rac-1-(4'-Chloro[1,1'-biphenyl]-4-yl)-1-(1H-imidaz...)
Affinity DataIC50: 29nMAssay Description:Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342174(rac-1-(4'-Chloro[1,1'-biphenyl]-4-yl)-1-(1H-imidaz...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed