BDBM50342191 (R)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)propyl)biphenyl-3-yl)acetamide::CHEMBL1766192

SMILES CC[C@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1

InChI Key InChIKey=LSNINMQJLNWRJL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342191   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342191((R)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)propyl)bi...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human 17,20 lyase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342191((R)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)propyl)bi...)
Affinity DataIC50: 450nMAssay Description:Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342191((R)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)propyl)bi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed