BDBM50342198 4-{5-Phenyl-3-[3-(3-trifluoromethyl-phenyl)-ureidomethyl]-pyrazol-1-yl}-benzenesulfonamide::CHEMBL1766295

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(CNC(=O)Nc2cccc(c2)C(F)(F)F)cc1-c1ccccc1

InChI Key InChIKey=IPBAGVOSINAMJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342198   

TargetBifunctional epoxide hydrolase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50342198(4-{5-Phenyl-3-[3-(3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50342198(4-{5-Phenyl-3-[3-(3-trifluoromethyl-phenyl)-ureido...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed