BDBM50342199 1-[5-tert-Butyl-1-(4-methanesulfonyl-phenyl)-1H-pyrazol-3-ylmethyl]-3-(3-trifluoromethyl-phenyl)-urea::CHEMBL1766296

SMILES CC(C)(C)c1cc(CNC(=O)Nc2cccc(c2)C(F)(F)F)nn1-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=HNQVOJXAYMEWDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342199   

TargetBifunctional epoxide hydrolase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50342199(1-[5-tert-Butyl-1-(4-methanesulfonyl-phenyl)-1H-py...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50342199(1-[5-tert-Butyl-1-(4-methanesulfonyl-phenyl)-1H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed