BDBM50342204 4-(5-p-Tolyl-3-{3-[3-(3-trifluoromethyl-phenyl)-ureido]-propyl}-pyrazol-1-yl)-benzenesulfonamide::CHEMBL1766301

SMILES Cc1ccc(cc1)-c1cc(CCCNC(=O)Nc2cccc(c2)C(F)(F)F)nn1-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=KPZWJSMDQMZGAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342204   

TargetBifunctional epoxide hydrolase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50342204(4-(5-p-Tolyl-3-{3-[3-(3-trifluoromethyl-phenyl)-ur...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 10 mins by fluorescent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50342204(4-(5-p-Tolyl-3-{3-[3-(3-trifluoromethyl-phenyl)-ur...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant COX-2 after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed