BDBM50342398 CHEMBL4163150::US11534443, Example 31

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1cc(OC2CCOCC2)c2nc(NCC3CC3)nc(C)c2c1

InChI Key InChIKey=DBTUXAQQDZKWMP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342398   

TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent

LigandBDBM50342398(CHEMBL4163150 | US11534443, Example 31)Copy SMILESCopy InChI

Affinity DataIC50: 3.80nMAssay Description:The Kinase-Glo Kinase Assay Kit was purchased from Promega. All assays were performed at room temperature using white OptiPlate -384 well plate. The ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/20/2023
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Peking Union Medical College

Curated by ChEMBL

LigandBDBM50342398(CHEMBL4163150 | US11534443, Example 31)Copy SMILESCopy InChI

Affinity DataIC50: 5.40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate by Kinase-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/14/2020
Entry Details Article
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