BDBM50342745 (R)-2-(5-(dimethylamino)naphthalene-1-sulfonamido)-3-(3,7,11-trimethyldodeca-2,6,10-trienylthio)propanoic acid::CHEMBL1771299

SMILES [#6]-[#7](-[#6])-c1cccc2c(cccc12)S(=O)(=O)[#7]-[#6@@H](-[#6]-[#16]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6](-[#8])=O

InChI Key InChIKey=SYZMIZZZSRKMGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342745   

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342745((R)-2-(5-(dimethylamino)naphthalene-1-sulfonamido)...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed