BDBM50342916 6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-((2-methylthiazol-4-yl)methyl)quinazolin-4-amine::CHEMBL1474834
SMILES CN(Cc1csc(C)n1)c1ncnc2ccc(cc12)-c1ccc2OCOc2c1
InChI Key InChIKey=PMDAVRLCSZSLRH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50342916
TargetDual specificity protein kinase CLK3(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of Clk3 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 19(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 190nMAssay Description:Binding affinity to human Ysk4 More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 340nMAssay Description:Binding affinity to human PIK3C2BMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 360nMAssay Description:Binding affinity to human PIP5K2C More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 370nMAssay Description:Binding affinity to human PIK3CG More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 15(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 430nMAssay Description:Binding affinity to human Erk8 More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 480nMAssay Description:Binding affinity to human Dyrk2 More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 5nMAssay Description:Binding affinity to human Clk4 More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 13nMAssay Description:Binding affinity to human Dyrk1A More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 18nMAssay Description:Binding affinity to human Clk1 More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Clk1 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of Dyrk1B kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase C2 domain-containing subunit gamma(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 40nMAssay Description:Binding affinity to human PIK3C2GMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 5(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 47nMAssay Description:Binding affinity to human Mek5 More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 59nMAssay Description:Binding affinity to human Clk2 More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataIC50: 186nMAssay Description:Inhibition of Clk2 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKd: 300nMAssay Description:Binding affinity to human Dyrk1B More data for this Ligand-Target Pair