BDBM50343232 CHEMBL1773559::N-(6-(2-(4-Methoxyphenylthio)pyrimidin-4-yl)benzo[d]thiazol-2-yl)acetamide

SMILES COc1ccc(Sc2nccc(n2)-c2ccc3nc(NC(C)=O)sc3c2)cc1

InChI Key InChIKey=CYLXABNZYVTFFR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343232   

LigandPNGBDBM50343232(CHEMBL1773559 | N-(6-(2-(4-Methoxyphenylthio)pyrim...)
Affinity DataKi:  18nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50343232(CHEMBL1773559 | N-(6-(2-(4-Methoxyphenylthio)pyrim...)
Affinity DataIC50:  3.01E+3nMAssay Description:Inhibition of mTOR assessed as inhibition of 4EBP1 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed