BDBM50343422 1-[2-Chloro-2-(4-fluorophenyl)ethyl]-N-(pyridin-4-ylmethyl)-1Hpyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1775047

SMILES Fc1ccc(cc1)C(Cl)Cn1ncc2c(NCc3ccncc3)ncnc12

InChI Key InChIKey=JKEOLUJTQXIYQJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343422   

TargetTyrosine-protein kinase ABL1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343422(1-[2-Chloro-2-(4-fluorophenyl)ethyl]-N-(pyridin-4-...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343422(1-[2-Chloro-2-(4-fluorophenyl)ethyl]-N-(pyridin-4-...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed